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Maintenance with PARP inhibitor is the way forward in ovarian cancer:Median PFS in platinum sensitive relapse carcinoma ovary is approximately 10 months.20% of high grade serous carcinoma ovary have somatic or germline mutation in BRCA gene.Sin

Now long term survival is possible in some stage IV solid cancers with the use of targeted, hormonal, chemotherapy drugs. The list includes:1) Stage IV hormone receptor positive metastatic breast cancer.2) Stage IV her2 nu positive metastatic breas

Bevacizumab is the first antiangiogenic therapy to be approved in advanced adenocarcinoma lung in combination with chemotherapy. Dose used in different trial was different and varied from 7.5 mg/kg 3 weekly to 15 mg/kg every 3 weeks. Chemotherapy par

ERA OF PERSONALISED MEDICINE IN METASTATIC ADENOCARCINOMA LUNG:Stage IV adenocarcinoma is not a single disease. Different molecular subtypes of NSCLC have been identified and the treatment approach is different for each subtype.The different mole

-CNS relapse is a rare but fatal event in NHL patients.- It seems to be rarer and later in rituximab era.-CNS prophylaxis is associated with sever neurotoxicity.-Risk scores to predict CNS relapse display low sensitivity.-Prophylaxis is recommend

A case report of newly diagnosed epithelial ovarian carcinoma presenting with spontaneous tumor lysis syndrome and its successful management with rasburicaseDr Deepak Kumar Shuklahttp://www.ijmpo.org/text.asp?2017/38/3/360/216841

Pregnancy and cancer: A challenge for obstetrician and oncologist!As the age of child birth is delayed we may be seeing more cases with cancer in pregnancy.At present estimated incidence of cancer in pregnancy is estimated to be around 1 in 1000

Decoding Lynch syndrome -- Colorectal cancer(CRC)Lynch syndrome is the most common cause of inherited Colorectal cancer (CRC-large intestine cancer). It constitutes 3% of all newly diagnosed colorectal cancer burden.In lynch syndrome there is ger

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