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Maintenance with PARP inhibitor is the way forward in ovarian cancer:Median PFS in platinum sensitive relapse carcinoma ovary is approximately 10 months.20% of high grade serous carcinoma ovary have somatic or germline mutation in BRCA gene.Sin
View DetailsERA OF PERSONALISED MEDICINE IN METASTATIC ADENOCARCINOMA LUNG:Stage IV adenocarcinoma is not a single disease. Different molecular subtypes of NSCLC have been identified and the treatment approach is different for each subtype.The different mole
View DetailsRedefining low grade glioma ( a type of brain tumor ) using WHO 2016 classification:Clinical presentation of low grade glioma is usually with new onset seizureRadiologically low grade glioma are hyperintense on T2 MRI images and do not show contr
View DetailsLiquid biopsy in non small cell lung cancer is now being used for detection of EGFR mutation analysis in patients who do not have accessible tissue for conventional testing and based on the platform used for liquid biopsy ie digital v/s nondigital it
View DetailsSoon in india 2 different CDK 4/6 inhibitors will be available thus widening treatment options for hormone positive metastatic breast cancer.CDK 4/6 inhibitors are new class of drugs recently approved for metastatic hormone positive breast cancer
View DetailsDecoding Lynch syndrome -- Colorectal cancer(CRC)Lynch syndrome is the most common cause of inherited Colorectal cancer (CRC-large intestine cancer). It constitutes 3% of all newly diagnosed colorectal cancer burden.In lynch syndrome there is ger
View DetailsTargeted therapy with gefitinib or erlotinib for 2 years is better than chemotherapy as adjuvant in resected non small cell lung cancer stage l to llla with EGFR mutation. The result suggest better disease free survival, however overall survival data
View DetailsAll cases of classical Hodgkin's lymphoma are CD 30 positive and LCA negative.CD 20 positivity and CD15 negative IHC profile on biopsy of lymph node is seen in around 10%.The presence of such an IHC profile should be kept in mind before diagnosis
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